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Total Synthesis of Complestatin: Development of a Pd(0)-mediated Indole Annulation for Macrocyclization

Full details of the initial development and continued examination of a powerful intramolecular palladium(0)-mediated indole annulation for macrocyclization closure of the strained 16-membered biaryl ring system found in complestatin (1, chloropeptin II) and the definition of factors impacting its in...

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Detalhes bibliográficos
Main Authors: Shimamura, Hiroyuki, Breazzano, Steven P., Garfunkle, Joie, Kimball, F. Scott, Trzupek, John D., Boger, Dale L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892899/
https://ncbi.nlm.nih.gov/pubmed/20469945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja102304p
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