A Nonviral Minicircle Vector for Deriving Human iPS Cells

Due to the risk of insertional mutagenesis, viral transduction has been increasingly replaced by non-viral methods to generate induced pluripotent stem (iPS) cells. One technique that has not yet been explored is the use of “minicircle” DNA, a novel compact vector that is free of bacterial DNA and c...

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Main Authors: Jia, Fangjun, Wilson, Kitchener D., Sun, Ning, Gupta, Deepak M., Huang, Mei, Li, Zongjin, Robbins, Robert C., Kay, Mark A., Longaker, Michael T., Wu, Joseph C.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892897/
https://ncbi.nlm.nih.gov/pubmed/20139967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1426
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