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Tumor-prone phenotype of the DDB2-deficient mice
DDB2 is an essential subunit of the damaged-DNA recognition factor DDB, which is involved in global genomic repair in human cells. Moreover, DDB2 is mutated in the repair-deficiency disease xeroderma pigmentosum (Group E). Expression of DDB2 in human cells is induced by P53, BRCA1 and by ionizing ra...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892891/ https://ncbi.nlm.nih.gov/pubmed/15558025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1208211 |
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