Acute Pharmacological Modulation of mGluR8 reduces measures of anxiety

Metabotropic glutamate receptors (mGluRs), which are coupled to second messenger pathways via G proteins, modulate glutamatergic and GABAergic neurotransmission. Because of their role in modulating neurotransmission, mGluRs are attractive therapeutic targets for anxiety disorders. Previously we show...

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Autori principali: Duvoisin, Robert M., Pfankuch, Tim, Wilson, Julie M., Grabell, Julie, Chhajlani, Vijay, Brown, Dean G., Johnson, Edwin, Raber, Jacob
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892883/
https://ncbi.nlm.nih.gov/pubmed/20385173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2010.04.006
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