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Pax2 and Pea3 synergize to activate a novel regulatory enhancer for spalt4 in the developing ear
The transcription factor spalt4 is a key early-response gene in otic placode induction. Here, we characterize the cis-regulatory regions of spalt4 responsible for activation of its expression in the developing otic placode and report the isolation of a novel core enhancer. Identification and mutatio...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892740/ https://ncbi.nlm.nih.gov/pubmed/19913005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.11.004 |
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