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Rapid Seizure-Induced Reduction of Benzodiazepine and Zn(2+) Sensitivity of Hippocampal Dentate Granule Cell GABA(A) Receptors

Fast synaptic inhibition in the forebrain is mediated primarily by GABA acting on GABA(A) receptors (GABARs). GABARs are regulated by numerous positive (barbiturates, benzodiazepines, and neurosteroids) and negative (picrotoxin, bicuculline, and Zn(2+)) allosteric modulators. The sensitivity of GABA...

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Detalhes bibliográficos
Main Authors: Kapur, Jaideep, Macdonald, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892718/
https://ncbi.nlm.nih.gov/pubmed/9295398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-19-07532.1997
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