Comparison of scores for bimodality of gene expression distributions and genome-wide evaluation of the prognostic relevance of high-scoring genes

BACKGROUND: A major goal of the analysis of high-dimensional RNA expression data from tumor tissue is to identify prognostic signatures for discriminating patient subgroups. For this purpose genome-wide identification of bimodally expressed genes from gene array data is relevant because distinguisha...

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Hauptverfasser: Hellwig, Birte, Hengstler, Jan G, Schmidt, Marcus, Gehrmann, Mathias C, Schormann, Wiebke, Rahnenführer, Jörg
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892466/
https://ncbi.nlm.nih.gov/pubmed/20500820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-276
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