PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-α target gene activation by regulating lysine demethylase 1 specificity

Histone methylation has a key role in oestrogen receptor (ERα)-mediated transactivation of genes. Proline glutamic acid and leucine-rich protein 1 (PELP1) is a new proto-oncogene that functions as an ERα co-regulator. In this study, we identified histone lysine demethylase, KDM1, as a new PELP1-inte...

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Detalhes bibliográficos
Main Authors: Nair, Sujit S, Nair, Binoj C, Cortez, Valerie, Chakravarty, Dimple, Metzger, Eric, Schüle, Roland, Brann, Darrell W, Tekmal, Rajeshwar R, Vadlamudi, Ratna K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892318/
https://ncbi.nlm.nih.gov/pubmed/20448663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.62
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