Human Plasmacytoid Dendritic Cell Accumulation Amplifies Their Type 1 Interferon Production

To determine the potential consequences of plasmacytoid dendritic cell (pDC) accumulation in tissue sites observed in several autoimmune diseases, we measured type 1 interferon production from circulating human pDCs as a function of pDC concentration. The effects of interferon-alpha and blockade of...

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Main Authors: Liao, Anne P, Salajegheh, Mohammad, Morehouse, Chris, Nazareno, Remedios, Jubin, Ronald G, Jallal, Bahija, Yao, Yihong, Greenberg, Steven A
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892243/
https://ncbi.nlm.nih.gov/pubmed/20346735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.02.014
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