Identification of Markers of Taxane Sensitivity Using Proteomic and Genomic Analyses of Breast Tumors from Patients Receiving Neoadjuvant Paclitaxel and Radiation

PURPOSE: To identify molecular markers of pathologic response to neoadjuvant paclitaxel/radiation treatment, protein and gene expression profiling were done on pretreatment biopsies. EXPERIMENTAL DESIGN: Patients with high-risk, operable breast cancer were treated with three cycles of paclitaxel fol...

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Detalhes bibliográficos
Main Authors: Bauer, Joshua A., Chakravarthy, A. Bapsi, Rosenbluth, Jennifer M., Mi, Deming, Seeley, Erin H., De Matos Granja-Ingram, Nara, Olivares, Maria G., Kelley, Mark C., Mayer, Ingrid A., Meszoely, Ingrid M., Means-Powell, Julie A., Johnson, Kimberly N., Tsai, Chiaojung Jillian, Ayers, Gregory D., Sanders, Melinda E., Schneider, Robert J., Formenti, Silvia C., Caprioli, Richard M., Pietenpol, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892225/
https://ncbi.nlm.nih.gov/pubmed/20068102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1091
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