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Spontaneous Autoimmunity in Mice That Carry an IghV Partial Transgene: A Required Arginine in VHCDR3
We describe a unique spontaneous mouse model of autoimmunity, which occurs on a nonautoimmune-prone SWR genetic background. In this model, SWR mice carry an IghV partial transgene encoding only the heavy chain variable domain of an antibody directed against chromatin. Autoimmune disease in partial t...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892212/ https://ncbi.nlm.nih.gov/pubmed/19276297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0961203308097480 |
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