Plaque and tangle imaging and cognition in normal aging and Alzheimer’s disease

Amyloid plaques and tau neurofibrillary tangles, the pathological hallmarks of Alzheimer’s disease (AD), begin accumulating in the healthy human brain decades before clinical dementia symptoms can be detected. There is great interest in how this pathology spreads in the living brain and its associat...

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Main Authors: Braskie, Meredith N., Klunder, Andrea D., Hayashi, Kiralee M., Protas, Hillary, Kepe, Vladimir, Miller, Karen J., Huang, S.-C., Barrio, Jorge R., Ercoli, Linda M., Siddarth, Prabha, Satyamurthy, Nagichettiar, Liu, Jie, Toga, Arthur W., Bookheimer, Susan Y., Small, Gary W., Thompson, Paul M.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891885/
https://ncbi.nlm.nih.gov/pubmed/19004525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2008.09.012
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