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Gene dosage affects the cardiac and brain phenotype in nonmuscle myosin II-B–depleted mice
Complete ablation of nonmuscle myosin heavy chain II-B (NMHC-B) in mice resulted in cardiac and brain defects that were lethal during embryonic development or on the day of birth. In this paper, we report on the generation of mice with decreased amounts of NMHC-B. First, we generated B(ΔI)/B(ΔI) mic...
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| Published in: | J Clin Invest |
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| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2000
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289177/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10712438/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8199 |
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