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SCN5A allelic expression imbalance in African-Americans heterozygous for the common variant p.Ser1103Tyr
BACKGROUND: Heterozygous and homozygous carriers of SCN5A-p.Ser1103Tyr, a common genetic variant with functional effects among African-Americans, have an increased risk of sudden death. We hypothesized that some heterozygous carriers may have unequal expression of wild-type and variant alleles and s...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891713/ https://ncbi.nlm.nih.gov/pubmed/20470418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-74 |
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