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Dynein light chain binding to a 3′-untranslated sequence mediates parathyroid hormone mRNA association with microtubules

The 3′-untranslated region (UTR) of mRNAs binds proteins that determine mRNA stability and localization. The 3′-UTR of parathyroid hormone (PTH) mRNA specifically binds cytoplasmic proteins. We screened an expression library for proteins that bind the PTH mRNA 3′-UTR, and the sequence of 1 clone was...

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Published in:J Clin Invest
Main Authors: Epstein, Eyal, Sela-Brown, Alin, Ringel, Israel, Kilav, Rachel, King, Stephen M., Benashski, Sharon E., Yisraeli, Joel K., Silver, Justin, Naveh-Many, Tally
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2000
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289163/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10683380/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8557
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