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The Drosophila cell cycle kinase PAN GU forms an active complex with PLUTONIUM and GNU to regulate embryonic divisions

Early embryonic cell cycles in Drosophila consist of rapidly alternating S and M phases. Three genes, pan gu (png), plutonium (plu), and giant nuclei (gnu) coordinate these early S-M cycles by ensuring adequate Cyclin B protein levels. Mutations in any of these genes result in unregulated DNA replic...

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Pubblicato in:Genes Dev
Autori principali: Lee, Laura A., Van Hoewyk, Douglas, Orr-Weaver, Terry L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289155/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14665672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1132603
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