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Antipermeability Function of PEDF Involves Blockade of the MAP Kinase/GSK/β-Catenin Signaling Pathway and uPAR Expression
PURPOSE. Pigment epithelium–derived factor (PEDF) is a potent inhibitor of vascular endothelial growth factor (VEGF)–induced endothelial permeability. The goal of this study was to understand the mechanism by which PEDF blocks VEGF-induced increases in vascular permeability. METHODS. The paracellula...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Association for Research in Vision and Ophthalmology, Inc.
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891479/ https://ncbi.nlm.nih.gov/pubmed/20089873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2878 |
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