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Treatment of Sheep Steroid–Induced Ocular Hypertension with a Glucocorticoid-Inducible MMP1 Gene Therapy Virus

PURPOSE. To investigate whether intracameral injection of the adenovirus vector AdhGRE.MMP1 would reduce or prevent elevated intraocular pressure (IOP) induced by corticosteroids in living animals. METHODS. Glucocorticoid-inducible adenovirus vectors carrying wild-type or mutant forms of human metal...

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Detalhes bibliográficos
Main Authors: Gerometta, Rosana, Spiga, Maria-Grazia, Borrás, Teresa, Candia, Oscar A.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891463/
https://ncbi.nlm.nih.gov/pubmed/20089869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4920
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