MUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progenies

The present study was undertaken to estimate the therapeutic benefit to down-regulate the MUC4 mucin for reversing chemoresistance of pancreatic cancer (PC) stem/progenitor cells and their progenies. The results have revealed that MUC4 mucin is overexpressed in CD133(+) and CD133(−) pancreatic cells...

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Hauptverfasser: Mimeault, Murielle, Johansson, Sonny L., Senapati, Shantibhusan, Momi, Navneet, Chakraborty, Subhankar, Batra, Surinder K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891434/
https://ncbi.nlm.nih.gov/pubmed/20303649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2010.02.015
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