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The GABA(B) receptor agonist baclofen administered into the median and dorsal raphe nuclei is rewarding as shown by intracranial self-administration and conditioned place preference in rats
RATIONALE: The midbrain raphe regions have long been implicated in affective processes and disorders. There is increasing evidence to suggest that the median (MR) and dorsal raphe nuclei (DR) tonically inhibit reward-related processes. OBJECTIVES: Stimulation of GABA(B) receptors in the midbrain rap...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891391/ https://ncbi.nlm.nih.gov/pubmed/20054525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-009-1757-3 |
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