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The precore gene of the woodchuck hepatitis virus genome is not essential for viral replication in the natural host.

A number of naturally occurring hepatitis B virus mutants that cannot synthesize the virus precore protein have been identified. Such mutants have been associated with more severe forms of hepatitis, including fulminant hepatitis. The most common mutation observed is a substitution of G to A in the...

詳細記述

保存先:
書誌詳細
主要な著者: Chen, H S, Kew, M C, Hornbuckle, W E, Tennant, B C, Cote, P J, Gerin, J L, Purcell, R H, Miller, R H
フォーマット: Artigo
言語:Inglês
出版事項: 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC289138/
https://ncbi.nlm.nih.gov/pubmed/1501300
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