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Rational Antibody-based HIV-1 Vaccine Design: Current Approaches and Future Directions

Many anti-viral vaccines elicit neutralizing antibodies as a correlate of protection. For HIV, given the huge variability of the virus, it is widely believed that the induction of a broadly neutralizing antibody (bNAb) response will be crucial in a successful vaccine against the virus. Unfortunately...

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Detalhes bibliográficos
Main Authors: Walker, Laura M., Burton, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891291/
https://ncbi.nlm.nih.gov/pubmed/20299194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.02.012
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