Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoprotein.

Monoclonal antibodies have been isolated from human immunodeficiency virus type 1 (HIV-1)-infected patients that recognize discontinuous epitopes on the gp120 envelope glycoprotein, that block gp120 interaction with the CD4 receptor, and that neutralize a variety of HIV-1 isolates. Using a panel of...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Thali, M, Furman, C, Ho, D D, Robinson, J, Tilley, S, Pinter, A, Sodroski, J
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1992
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289129/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1380099/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.9.5635-5641.1992
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