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Targeting Eicosanoids Pathway in Non-Small Cell Lung Cancer

Multiple lines of evidence suggest that cyclooxygenase-2 (COX-2) upregulation is an early event in the development of non-small cell lung cancer. Preclinical data indicate tumors with upregulation of COX-2 synthesize high levels of prostaglandin E(2) (PGE(2)) which in turn are associated with increa...

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Detalhes bibliográficos
Main Authors: Horn, Leora, Backlund, Michael, Johnson, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891200/
https://ncbi.nlm.nih.gov/pubmed/19409031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728220902915567
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