Detection of hypoxia in microscopic tumors using (131)I-labeled iodo-azomycin galactopyranoside ((131)I-IAZGP) digital autoradiography

PURPOSE: Previous studies have shown that tumors less than 1 mm diameter derived from HT29 colorectal cancer cells are extremely hypoxic when grown intraperitoneally or intradermally in nude mice, whereas those of greater size (approximately 1–4 mm diameter) are not significantly hypoxic. The object...

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Autori principali: Li, Xiao-Feng, Sun, Xiaorong, Ma, Yuanyuan, Suehiro, Makiko, Zhang, Mutian, Russell, James, Humm, John L., Ling, C. Clifton, O'Donoghue, Joseph A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891169/
https://ncbi.nlm.nih.gov/pubmed/19921184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-009-1310-y
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