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Lack of correlation between soluble CD4-induced shedding of the human immunodeficiency virus type 1 exterior envelope glycoprotein and subsequent membrane fusion events.

The noncovalent association of the gp120 and gp41 envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) is disrupted by soluble CD4 binding, resulting in shedding of the gp120 exterior envelope glycoprotein. This observation has led to the speculation that interaction of gp120 with t...

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Pubblicato in:J Virol
Autori principali: Thali, M, Furman, C, Helseth, E, Repke, H, Sodroski, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1992
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289110/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1501286/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.9.5516-5524.1992
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