Cys residues of the hepatitis B virus capsid protein are not essential for the assembly of viral core particles but can influence their stability.
In the spherical capsid of hepatitis B virus (HBV), intermolecular disulfide bonds cross-link the approximately 180 p21.5 capsid protein subunits into a stable lattice. In this study, we used mutant capsid proteins to investigate the role that disulfide bonds and the four p21.5 Cys residues (positio...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289095/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1501280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.9.5393-5398.1992 |
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