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Proteolytic cleavage of the reovirus sigma 3 protein results in enhanced double-stranded RNA-binding activity: identification of a repeated basic amino acid motif within the C-terminal binding region.

The reovirus capsid protein sigma 3 was examined for double-stranded RNA (dsRNA)-binding activity by Northwestern (RNA-protein) blot analysis. Treatment of virion-derived sigma 3 protein with Staphylococcus aureus V8 protease led to an increase in the dsRNA-binding activity associated with the C-ter...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Miller, J E, Samuel, C E
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289090/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1501278/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.9.5347-5356.1992
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