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Tubulin polyglutamylation is essential for airway ciliary function through the regulation of beating asymmetry

Airway epithelial cilia protect the mammalian respiratory system from harmful inhaled materials by providing the force necessary for effective mucociliary clearance. Ciliary beating is asymmetric, composed of clearly distinguished effective and recovery strokes. Neither the importance of nor the ess...

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Bibliographic Details
Main Authors: Ikegami, Koji, Sato, Showbu, Nakamura, Kenji, Ostrowski, Lawrence E., Setou, Mitsutoshi
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890849/
https://ncbi.nlm.nih.gov/pubmed/20498047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002128107
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