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Strong synaptic transmission impact by copy number variations in schizophrenia

Schizophrenia is a psychiatric disorder with onset in late adolescence and unclear etiology characterized by both positive and negative symptoms, as well as cognitive deficits. To identify copy number variations (CNVs) that increase the risk of schizophrenia, we performed a whole-genome CNV analysis...

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Main Authors: Glessner, Joseph T., Reilly, Muredach P., Kim, Cecilia E., Takahashi, Nagahide, Albano, Anthony, Hou, Cuiping, Bradfield, Jonathan P., Zhang, Haitao, Sleiman, Patrick M. A., Flory, James H., Imielinski, Marcin, Frackelton, Edward C., Chiavacci, Rosetta, Thomas, Kelly A., Garris, Maria, Otieno, Frederick G., Davidson, Michael, Weiser, Mark, Reichenberg, Abraham, Davis, Kenneth L., Friedman, Joseph I., Cappola, Thomas P., Margulies, Kenneth B., Rader, Daniel J., Grant, Struan F. A., Buxbaum, Joseph D., Gur, Raquel E., Hakonarson, Hakon
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2010
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890845/
https://ncbi.nlm.nih.gov/pubmed/20489179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000274107
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