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Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T

A histone H3 variant, H3T, is highly expressed in the testis, suggesting that it may play an important role in the chromatin reorganization required for meiosis and/or spermatogenesis. In the present study, we found that the nucleosome containing human H3T is significantly unstable both in vitro and...

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Autori principali: Tachiwana, Hiroaki, Kagawa, Wataru, Osakabe, Akihisa, Kawaguchi, Koichiro, Shiga, Tatsuya, Hayashi-Takanaka, Yoko, Kimura, Hiroshi, Kurumizaka, Hitoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890842/
https://ncbi.nlm.nih.gov/pubmed/20498094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003064107
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