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Exploiting the determinants of stochastic gene expression in Saccharomyces cerevisiae for genome-wide prediction of expression noise
Gene regulation is a process with many steps allowing for stochastic biochemical reactions, which leads to expression noise—i.e., the cell-to-cell stochastic fluctuation in protein abundance. Such expression noise can give rise to drastically diverse phenotypes, even within isogenic cell populations...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890810/ https://ncbi.nlm.nih.gov/pubmed/20489180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914302107 |
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