B-Raf(V600E) and thrombospondin-1 promote thyroid cancer progression

Although B-Raf(V600E) is the most common somatic mutation in papillary thyroid carcinoma (PTC), how it induces tumor aggressiveness is not fully understood. Using gene set enrichment analysis and in vitro and in vivo functional studies, we identified and validated a B-Raf(V600E) gene set signature a...

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Detalhes bibliográficos
Main Authors: Nucera, Carmelo, Porrello, Alessandro, Antonello, Zeus Andrea, Mekel, Michal, Nehs, Matthew A., Giordano, Thomas J., Gerald, Damien, Benjamin, Laura E., Priolo, Carmen, Puxeddu, Efisio, Finn, Stephen, Jarzab, Barbara, Hodin, Richard A., Pontecorvi, Alfredo, Nose, Vânia, Lawler, Jack, Parangi, Sareh
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890809/
https://ncbi.nlm.nih.gov/pubmed/20498063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004934107
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