B-Raf(V600E) and thrombospondin-1 promote thyroid cancer progression

Although B-Raf(V600E) is the most common somatic mutation in papillary thyroid carcinoma (PTC), how it induces tumor aggressiveness is not fully understood. Using gene set enrichment analysis and in vitro and in vivo functional studies, we identified and validated a B-Raf(V600E) gene set signature a...

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Bibliografiset tiedot
Päätekijät: Nucera, Carmelo, Porrello, Alessandro, Antonello, Zeus Andrea, Mekel, Michal, Nehs, Matthew A., Giordano, Thomas J., Gerald, Damien, Benjamin, Laura E., Priolo, Carmen, Puxeddu, Efisio, Finn, Stephen, Jarzab, Barbara, Hodin, Richard A., Pontecorvi, Alfredo, Nose, Vânia, Lawler, Jack, Parangi, Sareh
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2010
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890809/
https://ncbi.nlm.nih.gov/pubmed/20498063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004934107
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