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Oligoclonality and innate-like features in the TCR repertoire of type II NKT cells reactive to a β-linked self-glycolipid

TCR-mediated recognition of β-linked self-glycolipids bound to CD1d is poorly understood. Here, we have characterized the TCR repertoire of a CD1d-restricted type II NKT cell subset reactive to sulfatide involved in the regulation of autoimmunity and antitumor immunity. The sulfatide/CD1d-tetramer(+...

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Autors principals: Arrenberg, Philomena, Halder, Ramesh, Dai, Yang, Maricic, Igor, Kumar, Vipin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890761/
https://ncbi.nlm.nih.gov/pubmed/20534460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000576107
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