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Expansion of human NK-22 cells with IL-7, IL-2, and IL-1β reveals intrinsic functional plasticity

Natural killer-22 (NK-22) cells are a human NK cell subset situated in mucosal-associated lymphoid tissues that specialize in IL-22 secretion in response to IL-23. Here we investigated the cytokine requirements for NK-22 cell expansion. IL-7 maintained the sur-vival of NK-22 cells and IL-22 producti...

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Autori principali: Cella, Marina, Otero, Karel, Colonna, Marco
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890739/
https://ncbi.nlm.nih.gov/pubmed/20534450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005641107
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