A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease

BACKGROUND: The inability of aspirin (ASA) to adequately suppress platelet aggregation is associated with future risk of coronary artery disease (CAD). Heritability studies of agonist-induced platelet function phenotypes suggest that genetic variation may be responsible for ASA responsiveness. In th...

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Main Authors: Mathias, Rasika A, Kim, Yoonhee, Sung, Heejong, Yanek, Lisa R, Mantese, VJ, Hererra-Galeano, J Enrique, Ruczinski, Ingo, Wilson, Alexander F, Faraday, Nauder, Becker, Lewis C, Becker, Diane M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890666/
https://ncbi.nlm.nih.gov/pubmed/20529293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-3-22
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