HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment

BACKGROUND: In the absence of the Vpu protein, newly formed HIV-1 particles can remain attached to the surface of human cells due to the action of an interferon-inducible cellular restriction factor, BST-2/tetherin. Tetherin also restricts the release of other enveloped viral particles and is counte...

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Autori principali: Hauser, Heiko, Lopez, Lisa A, Yang, Su Jung, Oldenburg, Jill E, Exline, Colin M, Guatelli, John C, Cannon, Paula M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890665/
https://ncbi.nlm.nih.gov/pubmed/20529266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-51
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