Pharmacokinetics of Linezolid and Ertapenem in experimental parapneumonic pleural effusion

OBJECTIVE: To determine the extent of linezolid and ertapenem penetration into the empyemic fluid using a rabbit model of empyema. METHODS: An empyema was created via the intrapleural injection of Escherichia coli bacteria (ATCC 35218) into the pleural space of New Zealand white rabbits. After an em...

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Autors principals: Saroglou, Maria, Tryfon, Stavros, Ismailos, Georgios, Liapakis, Ioannis, Tzatzarakis, Manolis, Tsatsakis, Aristidis, Papalois, Apostolos, Bouros, Demosthenes
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890630/
https://ncbi.nlm.nih.gov/pubmed/20482752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-7-22
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