Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives

BACKGROUND: A maximum entropy approach is proposed to predict the cytotoxic effects of a panel of colchicine derivatives in several human cancer cell lines. Data was obtained from cytotoxicity assays performed with 21 drug molecules from the same family of colchicine compounds and correlate these re...

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Détails bibliographiques
Auteurs principaux: Tseng, Chih-Yuan, Mane, Jonathan Y, Winter, Philip, Johnson, Lorelei, Huzil, Torin, Izbicka, Elzbieta, Luduena, Richard F, Tuszynski, Jack A
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890610/
https://ncbi.nlm.nih.gov/pubmed/20509970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-131
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