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Human immunodeficiency virus type 1 major neutralizing determinant exposed on hepatitis B surface antigen particles is highly immunogenic in primates.

Hepatitis B surface antigen (HBsAg) produced by recombinant DNA technology is now widely and safely used worldwide for hepatitis B vaccination. We used the HBsAg particle as a carrier molecule for presentation of selected human immunodeficiency virus type 1 (HIV-1) determinants to the immune system....

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Main Authors: Schlienger, K, Mancini, M, Rivière, Y, Dormont, D, Tiollais, P, Michel, M L
格式: Artigo
語言:Inglês
出版: 1992
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC289060/
https://ncbi.nlm.nih.gov/pubmed/1548782
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