Presentation and immunogenicity of the hepatitis B surface antigen and a poliovirus neutralization antigen on mixed empty envelope particles.

Insertion of a synthetic DNA fragment encoding a poliovirus neutralization epitope into the S gene encoding the major envelope protein of hepatitis B virus has yielded hybrid (HBsPolioAg) particles closely resembling authentic 22-nm antigen (HBsAg) particles by expression of the modified gene in mam...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Delpeyroux, F, Peillon, N, Blondel, B, Crainic, R, Streeck, R E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253244/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2451759/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.5.1836-1839.1988
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