Comparative whole genome sequence analysis of wild-type and cidofovir-resistant monkeypoxvirus

We performed whole genome sequencing of a cidofovir {[(S)-1-(3-hydroxy-2-phosphonylmethoxy-propyl) cytosine] [HPMPC]}-resistant (CDV-R) strain of Monkeypoxvirus (MPV). Whole-genome comparison with the wild-type (WT) strain revealed 55 single-nucleotide polymorphisms (SNPs) and one tandem-repeat cont...

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Main Authors: Farlow, Jason, Ichou, Mohamed Ait, Huggins, John, Ibrahim, Sofi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890524/
https://ncbi.nlm.nih.gov/pubmed/20509894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-110
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