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Diversity of T-cell receptors in virus-specific cytotoxic T lymphocytes recognizing three distinct viral epitopes restricted by a single major histocompatibility complex molecule.

Cytotoxic T lymphocytes (CTL) recognize virus peptide fragments complexed with class I major histocompatibility complex (MHC) molecules on the surface of virus-infected cells. Recognition is mediated by a membrane-bound T-cell receptor (TCR) composed of alpha and beta chains. Studies of the CTL resp...

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Udgivet i:J Virol
Principais autores: Yanagi, Y, Tishon, A, Lewicki, H, Cubitt, B A, Oldstone, M B
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289052/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1372370/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.4.2527-2531.1992
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