Interference with Activator Protein-2 transcription factors leads to induction of apoptosis and an increase in chemo- and radiation-sensitivity in breast cancer cells

BACKGROUND: Activator Protein-2 (AP-2) transcription factors are critically involved in a variety of fundamental cellular processes such as proliferation, differentiation and apoptosis and have also been implicated in carcinogenesis. Expression of the family members AP-2α and AP-2γ is particularly w...

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Main Authors: Thewes, Verena, Orso, Francesca, Jäger, Richard, Eckert, Dawid, Schäfer, Sabine, Kirfel, Gregor, Garbe, Stephan, Taverna, Daniela, Schorle, Hubert
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890516/
https://ncbi.nlm.nih.gov/pubmed/20459791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-192
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