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Mechanism of interferon action: alpha and gamma interferons differentially affect mRNA levels of the catalytic subunit of protein kinase A and protein Mx in human cells.

Treatment of human HeLa and amnion U cells with gamma interferon (IFN-gamma), either alone or in combination with alpha interferon (IFN-alpha), reduced the steady-state level of mRNA encoding the catalytic (C) subunit of protein kinase A (PKA) as measured by Northern gel-blot (RNA) analysis. In addi...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Thomas, D C, Samuel, C E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289050/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1548777/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.4.2519-2522.1992
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