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The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus

Mutations in KCNQ2 and KCNQ3 voltage-gated potassium channels lead to neonatal epilepsy as a consequence of their key role in regulating neuronal excitability. Previous studies in the brain have focused primarily on these KCNQ family members, which contribute to M-currents and afterhyperpolarization...

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Hlavní autoři: Tzingounis, Anastassios V., Heidenreich, Matthias, Kharkovets, Tatjana, Spitzmaul, Guillermo, Jensen, Henrik S., Nicoll, Roger A., Jentsch, Thomas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890451/
https://ncbi.nlm.nih.gov/pubmed/20534576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004644107
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