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Function of Apollo (SNM1B) at telomere highlighted by a splice variant identified in a patient with Hoyeraal–Hreidarsson syndrome

Telomeres, the protein–DNA complexes at the ends of linear chromosomes, are protected and regulated by the shelterin molecules, the telomerase complex, and other accessory factors, among which is Apollo, a DNA repair factor of the β-lactamase/β-CASP family. Impaired telomere protection in humans cau...

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Autori principali: Touzot, Fabien, Callebaut, Isabelle, Soulier, Jean, Gaillard, Laetitia, Azerrad, Chantal, Durandy, Anne, Fischer, Alain, de Villartay, Jean-Pierre, Revy, Patrick
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890423/
https://ncbi.nlm.nih.gov/pubmed/20479256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914918107
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