A Single Nucleotide Polymorphism in STK11 Influences Insulin Sensitivity and Metformin Efficacy in Hyperinsulinemic Girls With Androgen Excess

OBJECTIVE: Serine-threonine kinase STK11 catalyzes the AMP-activated protein kinase complex. We tested the hypothesis that a gene variant in STK11 contributes to variation in insulin sensitivity and metformin efficacy. RESEARCH DESIGN AND METHODS: We studied the effects of a single nucleotide polymo...

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Autores principales: López-Bermejo, Abel, Díaz, Marta, Morán, Erica, de Zegher, Francis, Ibáñez, Lourdes
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2010
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890356/
https://ncbi.nlm.nih.gov/pubmed/20357370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc09-1750
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