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A general lack of compensation for gene dosage in yeast

Gene copy number variation has been discovered in humans, between related species, and in different cancer tissues, but it is unclear how much of this genomic-level variation leads to changes in the level of protein abundance. To address this, we eliminated one of the two genomic copies of 730 diffe...

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Detalhes bibliográficos
Main Authors: Springer, Michael, Weissman, Jonathan S, Kirschner, Marc W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890323/
https://ncbi.nlm.nih.gov/pubmed/20461075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.19
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