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Pathologies Associated with the p53 Response
Although p53 is a major cancer preventive factor, under certain extreme stress conditions it may induce severe pathologies. Analyses of animal models indicate that p53 is largely responsible for the toxicity of ionizing radiation or DNA damaging drugs contributing to hematopoietic component of acute...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890204/ https://ncbi.nlm.nih.gov/pubmed/20595398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a001180 |
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